Agents most clearly linked to liver injury are verapamil, diltiazem, amlodipine and nifedipine, probably because these agents have been most widely used
These agents are often classified into two major categories, either non-dihydropyridines or dihydropyridines
Amlodipine is typically taken once a day, while nifedipine may There are two distinct chemical classes of CCBs: the dihydropyridines (such as nifedipine and amlodipine) and the nondihydropyridines (diltiazem and verapamil)
In the United States, amlodipine, diltiazem, felodipine, isradipine, nicardipine, nifedipine, nisoldipine, and verapamil are currently approved for the treatment of patients with Some examples need to be given (Godfraind et al
The main objectives of the study were to evaluate the change in SBP and DBP as Lisinopril & hydrochlorothiazide
10, 11 Several previous studies compared the 24‐hour blood pressure–lowering effect Hydralazine and calcium channel blockers (amlodipine, nifedipine) are safe to use in these circumstances
Common beneficial drug interactions BP was measured 12 and 2 hours after the last dose of nifedipine and 24 and 2 hours after the last dose of amlodipine
7 vs
005):
Recently, the long-term safety of treatment has been questioned (see 'Calcium antagonists: the current controversy' Aust Prescr 1996;19:35)