ACTs (apart from artesunate-SP) are also highly effective for treatment of vivax malaria, and parenteral artesunate is highly effective in the severe vivax disease 31
Chloroquine chemoprophylaxis might provide benefit in protecting against malaria during pregnancy, but studies with larger sample sizes are needed to confirm
vivax, or chloroquine-sensitive P
The mechanism of resistance and its molecular basis have proved elusive
According to WHO recommendations on treatment of chloroquine-resistant falciparum malaria in Malaria remains one of the most preventable causes of adverse birth outcomes
According to the US CDC, this drug is the drug of choice for the treatment of chloroquine-sensitive malaria species during pregnancy; it is also the drug of choice
Most recently, resistance to the artemisinin and non-artemisinin components of artemisinin-based combination therapy has emerged in parts of Southeast Asia, impacting the
Given the inhibition of autophagy and its immunomodulatory action, CQ shows positive efficacy against cancer
[PMC free article] [Google Scholar] Chou A
This review evaluated the adherence of the national guidelines drawn from World Health Organization (WHO) regions, Africa, Eastern Mediterranean, Southeast Asia, and Western Pacific, to the WHO recommendations on
The other first-line treatment for malaria caused by chloroquine-resistant P
However, reports of chloroquine-resistant parasites in pregnant women suggest that alternative treatment guidelines are needed to prevent repeated A prospective clinical study in eastern Sudan described the efficacy and toxicity of quinine in early pregnancy in mothers with chloroquine-resistant falciparum malaria
Reduced drug pressure resulted in substantial restoration of chloroquine susceptibility in malaria-endemic regions Resistance to sulfadoxine pyrimethamine
Chloroquine is a medication primarily used to prevent and treat malaria in areas where malaria remains sensitive to its effects
falciparum malaria in the most sub-Saharan countries until after 2,000 despite its declining use ( Flegg et al
Randomized comparison of mefloquine‐artesunate versus quinine in the treatment of multidrug‐resistant falciparum malaria in pregnancy
Mefloquine is the agent of choice for chloroquine-resistant areas, and evidence suggests it is not associated with an increased risk to the fetus
Chloroquine resistant or unknown resistance (All malaria- endemic regions except those in Central laterAmerica west of Panama Canal, Haiti, and 7 Primaquine andtafenoquine must not be used during pregnancy; pregnant patients with P
Evidence of chloroquine resistance was detected first in a traveller returning from Papua New Guinea over 30 years ago [5,6]
Summary; Full Text PDF; PubMed; were examined as part of a treatment study on atovaquone-proguanil-artesunate combination therapy for multidrug-resistant P falciparum malaria in pregnant women in the second and third The choice of a drug for a person traveling to areas where there is chloroquine-resistant malaria depends on traveler-related factors, 26 Pregnant Women