Context and Policy Issues
It plays a role as a “reward center” and in many body functions, including memory, movement, motivation, mood, attention and more
NE, as with dopamine, exhibits an inverted U influence on PFC cognitive functions
Doctors typically prescribe these drugs for people who have problems when The abuse of cocaine causes a powerful surge of dopamine in the nucleus accumbens and creates a shortcut to the brain’s pleasure center
In a study investigating the effects of clonidine in MDD patients and healthy controls, clonidine was shown to impair memory consolidation (word list learning) but did not affect working memory or memory retrieval
Keep in mind that dopamine isn’t acting alone
For both ligands, statistical parametric mapping showed that specific binding was lower in ADHD than in controls (threshold for significance set at P<
) administration of mirtazapine (5 and 10 mg/kg) increased extracellular dopamine, DOPAC and noradrenaline to approximately the same extent in both cortices, an effect totally suppressed by the alpha(2)-adrenoceptors agonist clonidine (0
The patient was started on oral DPH 50 mg 4 times a day and the dose was reduced by 25% every 3 days
This report examined the beneficial effects of clonidine on an adolescent female patient with OCD, suggesting therapeutic potential and highlighting the
2015; 32 (11 Extrapyramidal side effects (EPS), commonly referred to as drug-induced movement disorders are among the most common adverse drug effects patients experience from dopamine-receptor blocking agents
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