Danazol works by preventing the
Initially, 200 mg given 2 or 3 times daily until a favorable response (i
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Maintenance dose: Gradual downward titrations should be performed to maintain
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur
Endometriosis is a condition where tissue that normally lines the inside of your womb (uterus) is found elsewhere in your body, often in the pelvic area or abdomen
Drug Categories
This drug is given orally
However, due to the severe androgenic side effects and to the marketing of other drugs, the use of danazol significantly declined in the last 20 years [8, 9]
Clinicians and pharmacists should maintain a watchful eye for drug interactions and combined toxicity
The medicines below all contain the following active ingredient(s): danazol
Food and Drug Administration (FDA) as the first drug to specifically treat endometriosis, but its role as a treatment for endometriosis has been largely replaced by the gonadotropin-releasing hormone (GnRH) agonists
Avoid combinations; the risk of the interaction outweighs the benefit
Danazol is known to be associated with a risk of virilisation of the female foetus if administered during pregnancy
Information on such adverse effects, if any, has been given in the Danazol related warnings section
25 major drug interactions (53 brand and generic names); 202 moderate drug interactions (622 brand and generic names); 22 minor drug interactions (51 brand and generic names); A total of 249 drugs are known to interact