McCullough still recommends treating COVID-19 patients with hydroxychloroquine and ivermectin, even though both have been shown not to work
To provide evidence that serotonergic signaling mediates the ivermectin-induced phenotype, Lobikin et al blocked the function of different serotonin receptors and found
Approved for human use in 1987, it is used to treat infestations including
gov were
Evaluation of ivermectin is continuing in 31 ongoing trials, and we will update this review again when their results become available
Asymptomatic or
More recently however, several studies have documented antiviral effects of ivermectin and the potential to repurpose it as a therapeutic agent for viral infections [1, 2, 3]
2
1 Our article included randomized and observational trial meta-analyses on the efficacy of ivermectin for the
A macrocyclic lactone of multifaceted potency [2,3], IVM as deployed worldwide since 1987 has made major
Ivermectin
Early reviews recommended the use of ivermectin based largely on non-peer-reviewed evidence, which may not be robust
Ivermectin is an antiinfective agent with activity against several parasitic nematodes and scabies and is the treatment of choice for onchocerciasis (river blindness)
Since the above primary studies were published, many hundreds of thousands of patients 7 have been dosed with ivermectin, relying on an evidence base that has substantially evaporated under close Postpublication review confirmed that while the review article appropriately describes the mechanism of action of ivermectin, the cited sources do not appear to show that there is clear clinical evidence of the effect of