5 min read As breast cancer treatments improve, more women are living longer with the
Bisphosphonates are drugs that are used for a number of reasons
In terms of the absolute benefit, bisphosphonates decreased the breast cancer mortality rate from 18
Radiation Therapy Radiation therapy is used to kill cancer cells that may be left in the breast after surgery, and it can also increase the risk of bone loss and fractures Purpose To make recommendations regarding the use of bisphosphonates and other bone-modifying agents as adjuvant therapy for patients with breast cancer
Chemotherapy induced amenorrhea and the use of anti-estrogens can promote bone loss; thus, the management of bone health in women with
There are several guidelines that have already been published for bone-directed treatment, and Hadji et al
These medicines are called 'bisphosphonates'
This activity will highlight the mechanism of action, adverse event profile, and other key factors (e
Prevention
Any thoughts on what might be best? ANSWER: Oral bisphosphonate drugs — including alendronate (Fosamax), risedronate (Actonel and Atelvia) and ibandronate (Boniva) — are the most commonly prescribed osteoporosis drugs
However, it’s also possible to experience severe bone pain from taking Fosamax
Data are limited on the incidence of osteopenia, an earlier indicator of bone loss, and osteoporosis in younger breast cancer survivors compared with cancer-free women
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Treatment Guidelines for Patients With Breast Cancer on Aromatase Inhibitor Therapy
Aromatase inhibitors, which are commonly used to treat breast cancer, can also cause bone loss
Sometimes bisphosphonates are called bone strengthening or bone hardening treatments
As more women are exposed to AIs, it is important to understand their adverse effects on the skeleton
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