Allopurinol suicide inhibition

Allopurinol is itself oxidized by XDH and the product, oxypurinol, binds tightly to the reduced molybdenum centre of the enzyme, acting as a suicide inhibitor. These Suicide inhibition is an unusual type of irreversible inhibition where the enzyme converts the inhibitor into a reactive form in its active site

2024-03-29
    Tacrolimus therapeutic dose
  1. a change in or loss of taste
  2. Hitchings, shared with British scientist James W
  3. 55 ± 0
  4. Effects of Allopurinol on Secondary Outcomes
  5. Allopurinol reduces levels of uric acid in the blood and urine
  6. How and when to take it
  7. 11: Enzyme Inhibition
  8. Allopurinol is used to treat hyperuricemia and gout
  9. 1146/annurev