Modafinil displayed affinity ratios similar to those of benztropine, GBR12909 and bupropion (which lack cocaine-like effects in humans), but far different than those of
However, due to the increased exposure of hydroxybupropion over bupropion itself, which has higher affinity for the NET than the DAT, bupropion's overall pharmacological
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Hence, except for bupropion and GBR 12,909, for which NET-(DAT S1) induced an unexpected loss of binding affinity (Supporting Table S3), the binding data
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Bupropion is an atypical antidepressant medication
It is currently FDA-approved for treating major depressive disorder, seasonal affective disorder, and smoking cessation with several off-label uses, including sexual dysfunction secondary to antidepressant
Bupropion is a weak blocker of the neuronal uptake of serotonin, dopamine and norepinephrine and is a central nicotinic acetylcholine
WELLBUTRIN is supplied for oral administration as 75-mg (yellow-gold) and 100-mg (red) film-coated tablets
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frequent need to urinate
liver disease
Call your doctor for medical advice about side effects
Combining alcohol with bupropion may intensify the following side effects: drowsiness
dry mouth
Taking bupropion while breastfeeding is not expected to cause harmful effects for most breastfed infants
Wellbutrin, and its active ingredient bupropion, are sometimes considered for off-label use in ADHD